The study of thinking machines teaches us more about the brain than we can learn by introspective methods… — William S. Burroughs

Americans have a special horror of giving up control, of letting things happen in their own way without interference. They would like to jump down into their stomachs and digest the food and shovel the shit out.

Shooting PG is a terrible hassle, you have to burn out the alcohol first, then freeze out the camphor and draw this brown liquid off with a dropper—have to shoot it in the vein or you get an abscess, and usually end up with an abscess no matter where you shoot it. Best deal is to drink it with goof balls ... So we pour it in a Pernod bottle and start for New Orleans past iridescent lakes and orange gas flares, and swamps and garbage heaps, alligators crawling around in broken bottles and tin cans, neon arabesques of motels, marooned pimps scream obscenities at passing cars from islands of rubbish ... New Orleans is a dead museum. We walk around Exchange Place breathing PG and find The Man right away. It's a small place and the fuzz always knows who is pushing so he figures what the hell does it matter and sells to anybody. We stock up on H and backtrack for Mexico. Back through Lake Charles and the dead slot-machine country, south end of Texas, nigger-killing sheriffs look us over and check the car papers. Something falls off you when you cross the border into Mexico, and suddenly the landscape hits you straight with nothing between you and it, desert and mountains and vultures; little wheeling specks and others so close you can hear wings cut the air (a dry husking sound), and when they spot something they pour out of the blue sky, that shattering bloody blue sky of Mexico, down in a black funnel ... Drove all night, came at dawn to a warm misty place, barking dogs and the sound of running water.

The face of "evil" is always the face of total need. A dope fiend is a man in total need of dope. Beyond a certain frequency need knows absolutely no limit or control. In the words of total need: "Wouldn't you?" Yes you would. You would lie, cheat, inform on your friends, steal, do anything to satisfy total need. Because you would be in a state of total sickness, total possession, and not in a position to act in any other way. Dope fiends are sick people who cannot act other than they do. A rabid dog cannot choose but bite.